UK Pharmacogenetics & Stratified Medicine Network 11th Open Meeting



At UK Pharmacogenetics & Stratified Medicine Network (UKPGx) 11th Annual Open Meeting (UKPGx2024) you will hear about the latest developments in the field of pharmacogenetics and stratified medicine. Multidisciplinary experts will come together to review, and offer solutions to, the challenges facing the adoption of genomic medicine into the clinic.


Over the last 10 years the Network has steadily grown to over 1,200 members. It provides a great opportunity for different disciplines to come together and develop productive collaborations. You are most welcome to join the Network, membership is free, just contact UKPGx membership on ukpgx@bps.ac.uk.

This last year invited experts from academia, healthcare, regulatory and industry sectors came together to discuss Incorporating Pharmacogenetics into Clinical Decision Support Systems and Pharmacogenetics in Drug Discovery. Presentations from these workshops are available on our website. The presentations from all our past open meetings and workshops provide a wealth of information and can be viewed on the website.

 

08:00-09:00      Registration and Refreshments
09:00 - 10:40                Session One Opening Plenary Session
Chair: Professor Sir Munir Pirmohamed
09:00 - 09:10 Welcome & introduction: Professor Sir Munir Pirmohamed
09:10 - 09:40 Professor Dame Sue Hill
Accelerating genomic medicine in the NHS
09:40 - 10:10 Professor Nick Wareham
The changing landscape of cohort studies in the UK
10:10 - 10:40 Professor Raghib Ali
Our Future Health and opportunities for pharmacogenomic and precision public health research
10:40 - 11:10 Morning Coffee
11:10 - 12:10 Session Two Early Career Session
Chair: Vicky Chaplin
11:10 - 11:30 Dr Emma Magavern
Pharmacogenomics in Cardiovascular Medicine:
Insights from a British- South Asian cohort
11:30 - 11:50 Dr John McDermott
Developing an Interoperable and Scalable Platform for the 
Implementation of Pharmacogenetics in the NHS 
11:50 - 12:10 ECR
Talk title to be confirmed
12:10 - 13:30 Lunch, Exhibitors stand and Discussion Tables 
13:30 - 15:00   Session Three Mendelian Randomisation
Chair: Professor Ann Daly
13:30 - 14:00 Dr Verena Zuber
Mendelian randomisation strengths and limitations
14:00 - 14:30 Aroon Hingorani
Mendelian Randomization and drug development
14:30 - 15:00 Michael Johnson
Single-cell Mendelian Randomization for target and casual 
biomarker discovery
15:00 - 15:30 Afternoon Tea
15:30 - 17:10 Session Four New Technology Platforms
Chair: Dr Karen Spink
15:30 - 16:00 Dr Greet De Baets
AI in target identification and patient stratification
16:00 - 16:30 Professor Julian Knight
Moving to precision medicine in severe infection using host multi-omics 
16:30 - 17:00 Dr Vin Diwakar
Title to be confirmed
17:00 - 17:10 Professor Sir Munir Pirmohamed
Event Close and Thank You

Professor Sir Munir Pirmohamed



Professor Sir Munir Pirmohamed MB ChB, PhD, FRCPE, FRCP, FBPhS, FMedSci is David Weatherall Chair in Medicine at the University of Liverpool, and a Consultant Physician at the Royal Liverpool University Hospital. He is Director of the Centre for Drug Safety Sciences, and Director of the Wolfson Centre for Personalised Medicine. He is also Director of HDR North. He is an inaugural NIHR Senior Investigator, Fellow of the Academy of Medical Sciences in the UK, Commissioner on Human Medicines. He was President of British Pharmacological Society from January 2020 - December 2021, and is currently President of the Association of Physicians. He was awarded a Knights Bachelor in the Queen's Birthday Honours 2015. His research focuses on personalised medicine, clinical pharmacology and drug safety.

Dr John McDermott

Talk Title: Developing an Interoperable and Scalable Platform for the Implementation of Pharmacogenetics in the NHS

Dr John McDermott is a Clinical Geneticist and an NIHR Doctoral Research Fellow at the University of Manchester. He was appointed as the UK’s first Academic Clinical Fellow in Genomic Medicine in 2016. Working at the Manchester Centre for Genomic Medicine (MCGM) his research focuses on the application genetic and genomic technologies in the acute and everyday healthcare settings. As part of the Newman Laboratory he was awarded funding from the National Institute for Health Research (NIHR) to undertake the world’s first trial of a genetic test in the acute setting to avoid hearing loss in neonates. The Pharmacogenetics to Avoid Loss of Hearing (PALOH) trial and other similar projects require extensive collaboration between industry, academia and clinicians. This collaborative approach is encouraged at the MCGM and in 2018 Dr McDermott was awarded the NIHR Clinical Research Network award for outstanding contribution to UK research. In 2015 Dr McDermott was a visiting scholar at the MIT and Harvard Broad Institute where he first worked with large “multi-omic” datasets. In 2018 he was awarded the Vienna Medal by the European Society of Human Genetics for his translational research. He is a University of Manchester alumnus and is passionate about the unique opportunities for population health research across the region.  Dr McDermott is currently an NIHR Doctoral Research Fellow, investigating models for implementing pharmacogenetics within the NHS. (@John_H_McD)
 

Professor Aroon Hingorani


 

Professor of Genetic Epidemiology and Honorary Consultant Physician at UCL and UCL Hospitals
Talk Title: Mandelian Randomization and drug development

Aroon Hingorani is UCL Professor of Genetic Epidemiology; former Director of the UCL Institute of Cardiovascular Science (2011-2021); Cardiovascular Programme Lead for the UCL Hospitals NIHR Biomedical Research Centre; Director of the UCL British Heart Foundation Research Accelerator; and Principal Investigator of the UKRI-NIHR-DHSC funded Multimorbidity Mechanisms and Therapeutics Research Collaborative. He is Consultant Physician at University College London Hospitals NHS Foundation Trust with subspecialty accreditation in Clinical Pharmacology and Therapeutics. He chairs the North Central London Joint Formulary Committee and is an NIHR Senior Investigator.
His current work focuses on the use of genetic studies in populations as a tool to identify and validate drug targets, using the Mendelian randomisation principle, to improve efficiency in pharmaceutical development. He also has an interest in critical evaluation of the use of genomic and biomarker data for disease prediction and stratification and in the causes and management of multimorbidity.
Professor Hingorani has been a member of NICE guideline development groups on the prevention of thromboembolism in hospitalised patients and on lipid lowering for the prevention of cardiovascular disease.

 

Professor Michael Johnson DPhil FRACP FRCP



Professor of Neurology and Genomic Medicine at Imperial College London
Talk Title: Single-cell Mendelian randomization for target and casual biomarker discovery

Professor Johnson is Professor of Neurology and Genomic Medicine at Imperial College London, and Honorary Consultant Neurologist at Imperial College Healthcare. His academic research focuses on systems-level data integration to identify cell-type specific causal genes and biomarkers. His work has resulted in drug target and therapeutic use patent applications, enduring pharma collaborations, and a successful biotech spin-out. He sits on the Executive Management Committee for the Department of Brain Sciences at Imperial College, where he has previously served as Deputy Head of the Division of Clinical Translation and Interim Head of the Division of Neurology. He is Co-Lead for the Advanced Therapeutics theme in the newly created UK Epilepsy Research Institute. His research is funded by the MRC, Parkinson’s UK and several global Pharma including long-term support from UCB and Roche for molecular causal inference. 

We're excited to unveil our partnership opportunities! For more information on how to participate please download our - Partnership Prospectus 

If you have any questions or wish to connect with a member of the events team, please contact meetings@bps.ac.uk.
 

Confirmed Partners

                           



The Royal College of Physicians building is situated on St Andrews Place opposite Regent’s Park. They are a five-minute walk from Regent’s Park station or Great Portland Street station. Thye have a lift platform for wheelchair access at the entrance.

There are a great range of 3, 4 and 5 star hotels in close proximity to RCP London Events. Their recommended hotel booking agent has negotiated discounted rates with local hotels for both individuals and group bookings. For more information and for a list of current hotels and rates, please contact:
Jen Herbert
Diversity Travel
Tel: 0161 235 5413
Email: rcpevents@diversitytravel.com

Royal College of Physicians 
11 St Andrews Place
Regent's Park
London
NW1 4LE

 

Tickets


Early Career Researcher Non-Member Ticket £50.00
General Registration Non-Member Ticket £115.00
Industry Registration Non-Member Ticket £265.00


12:00 – 13:00 Registration and refreshments 
 
13:00 – 14:45   
 
Session One: History of BJCP
Session Chairs: Professor Robin Ferner, Professor Robert Flanagan and Professor Robert Bies 

 
13:00 – 13:05 Welcome & introduction: Professor Sir Mark Caulfield
 
13:05 – 13:35 Professor Tilli Tansey
Clinical Pharmacology post second world war

 
13:35 – 14:15 Professor Geoffrey Tucker, Dr Jeffrey Aronson, Professor James Ritter and Professor Adam Cohen
History of BJCP

 
14:15 – 14:30 Professor Serge Cremers, Dr Andrew Webb and Professor Robert Likic
Present day and future of BJCP

 
14:30 – 14:45 Professor James Dear
BJCP and Toxicology

 
14:45 – 15:15 Refreshment break
 
15:15 – 17:00 Session Two: History In The Making
Session Chairs: Professor Reecha Sofat, Dr Emma Magavern and Dr James Fullerton

 
15:15 – 15:35 Professor Michael Rieder and Professor Catriona Waitt
BJCP and Global Outreach

 
15:35 – 15:55 Generation R
BJCP and Patient Advocacy

 
15:55 – 16:15 Professor Ann Daly
BJCP and Personalised Medicine

 
16:15 – 16:35 Professor Oscar Della Pasqua, Dr Daniel Marks and Professor Geert Jan Groeneveld 
BJCP and Clinical Drug Development

 
16:35 – 17:00 Dame June Raine
MHRA and Clinical Pharmacology

 
17:00 – 17:05 Professor Sir Munir Pirmohamed
Closing remarks

 
From
26 June 2024
To
26 June 2024



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